The company was founded in 1755 by Jean-Marc Vacheron, an independent watchmaker in Geneva, Switzerland. This makes it one of the oldest watch manufacturer in the world with an uninterrupted history. Besides being a young businessman, Vacheron was also a talented craftsman. In 1770 his company created the first complication, and nine years later he designed the first engine-turned dials.
The son of Jean-Marc Vacheron, Abraham, took over the family business in 1785. During this period the company was able to survive the French Revolution (1789–1799). Later, in 1810, Jaques-Barthelemy Vacheron, the grandson of the founder, became the head of the company. He was the first to initiate the company's exports to France and Italy.
Later, Jaques-Barthélemy realized that he was not able to handle his business alone. In order to travel overseas and sell the company's products, he needed a partner. Consequently, in 1819 Francois Constantin became the associate of Vacheron. The company continued its activity under the name Vacheron & Constantin.
Vacheron Constantin is considered to be company that was able to create one of the most complicated wristwatches in the world entitled "Tour de I'lle". It was created in 2005 to mark the anniversary of 250 years of Vacheron Constantin. The watch includes 834 parts and 16 horological complications.